Cetrorelix acetate

1.Cetrorik is A synthetic gonadotropin-releasing hormone (GnRH) antagonist (GNRH-A) drug. The indications are for patients undergoing controlled ovarian stimulation, preventing early ovulation, and then ovulation collection and assisted reproductive technology treatment, which has been listed in 45 countries including Europe and entered China in 2010.

2. For many years, only the original drug Cetronic acetate for injection in the domestic market was sold, and it was not until 2018 that a small number of domestic products broke the monopoly. However, it is still in a state of under-saturation.

Leuprelin

1. Leuprelin acetate microspheres for injection, mainly composed of leuprelin acetate, are gonadotropin-releasing hormone agonists, in white or white-like particles or powder form. The drug is mainly used to treat endometriosis, uterine fibroids, breast cancer, prostate cancer, central precocious puberty and other diseases.

2. From 2010 to 2021, US sales of leprerelin microsphere varieties for injection have remained at about $800 million for more than a decade. It entered the Chinese market around 2000. The terminal sales of leuprelin acetate microspheres in China's public medical institutions increased from $83 million in 2013 to $600 million in 2021, with a CAGR of 24.44% in the past five years